Nos publications

@article{PERROT2025,

title = {Survival, Years of Life Lost and Attrition Rates in Multiple Myeloma Patients in France},

author = {Aurore Perrot and Fanny Raguideau and Helene Denis and Martin Prodel and Matthieu Javelot and Marie Pierres and Cyrille Touzeau},

url = {https://www.sciencedirect.com/science/article/pii/S2152265025000801},

doi = {https://doi.org/10.1016/j.clml.2025.03.004},

issn = {2152-2650},

year  = {2025},

date = {2025-01-01},

urldate = {2025-01-01},

journal = {Clinical Lymphoma Myeloma and Leukemia},

abstract = {Background 

In a context of strong evolution of multiple myeloma (MM) treatment paradigm, real-world data allow a better understandingthe patients' medical needs. 

Methods 

The present analyses from the MYLORD study were designed to provide recent data on MM patients: characteristics, overall survival (OS), years of life lost (YLL) and attrition rates, using the French National Health Insurance Database (SNDS). It is based on a cohort of 33,032 MM patients who initiated a frontline therapy from 2014 to 2021 in France and who were followed until 2021. 

Results 

The 5-year OS rate is estimated at 51.9% (95% CI: 51.2–52.6). This rate is 78.3% (95% CI: 77.1–79.5) for patients with frontline autologous stem cell transplant (L1T) and 43.6% (95% CI: 42.8–44.4) for those without transplant (L1NT). The excess of mortality in MM patients is revealed by 12.3 YLL versus the matched general population and is higher in L1T patients than those L1NT (17 vs. 11 years). The attrition rate is important in MM patients with 38% of patients who did not benefit from at least 2 lines of treatment and is higher in L1NT patients than those in L1T (41% vs. 29%). Also, the majority of L1NT patients did not receive a L2 because of death, whereas it is because of stay in line status for L1T patients. 

Conclusion 

These results emphasize the urgency to treat MM patients with the best and tailored treatment strategy available, for all MM patients beneficiating or not from a transplant in frontline therapy. Further studies will be needed to assess the impact of new therapeutic options in real life.},

keywords = {biostatistics, pathways},

pubstate = {published},

tppubtype = {article}

}

@article{laurent2019analyses,

title = {Analyses des séquences de traitements à partir du SNIIRAM: cas d’étude des incidents 2013 du VIH},

author = {Marie Laurent and Lucie Leotoing and Martin Prodel},

year  = {2019},

date = {2019-01-01},

urldate = {2019-01-01},

journal = {Revue d'Épidémiologie et de Santé Publique},

volume = {67},

pages = {S177–S178},

publisher = {Elsevier},

keywords = {biostatistics, machine learning},

pubstate = {published},

tppubtype = {article}

}

@article{lawton2019cost,

title = {Cost-of-illness of inflammatory bowel disease patients treated with anti-tumour necrosis factor: A French large single-centre experience},

author = {Jean Lawton and Hamza Achit and Lieven Pouillon and Emmanuelle Boschetti and Béatrice Demore and Thierry Matton and Charlène Tournier and Martin Prodel and Laurent Peyrin-Biroulet and Francis Guillemin},

year  = {2019},

date = {2019-01-01},

urldate = {2019-01-01},

journal = {United European Gastroenterology Journal},

volume = {7},

number = {7},

pages = {908–913},

publisher = {SAGE Publications Sage UK: London, England},

keywords = {biostatistics},

pubstate = {published},

tppubtype = {article}

}

@article{genreau2019pin35,

title = {Global annual costs of people living with HIV in France in 2013 from a national insurance claims database (Sniiram)},

author = {Marie Genreau and Martin Prodel and Lucie Léotoing and Laurent Finkielsztejn and Gaëlle Nachbaur and Laetitia Roustand and Jade Ghosn and Fabrice Bonnet},

year  = {2019},

date = {2019-01-01},

urldate = {2019-01-01},

journal = {Value in Health},

volume = {22},

pages = {S645–S646},

publisher = {Elsevier},

keywords = {biostatistics},

pubstate = {published},

tppubtype = {article}

}

@article{bourgoin2015effects,

title = {Effects of moderate hyperbilirubinemia on nutritive swallowing and swallowing-breathing coordination in preterm lambs},

author = {Mélisande Bourgoin-Heck and Marie-Laure Specq and Nathalie Samson and Charlène Nadeau and Martin Prodel and François Corbin and Jean-Paul Praud},

year  = {2015},

date = {2015-01-01},

urldate = {2015-01-01},

journal = {Neonatology},

volume = {108},

number = {1},

pages = {42–48},

publisher = {S. Karger AG},

keywords = {biostatistics},

pubstate = {published},

tppubtype = {article}

}

@article{bourgoin2014sfp,

title = {Effet d’une hyperbilirubinémie sur la déglutition et la coordination déglutition-respiration chez l’agneau prématuré},

author = {Mélisande Bourgoin-Heck and ML Specq and N Samson and Martin Prodel and C Nadeau and François Corbin and JP Praud},

year  = {2014},

date = {2014-01-01},

urldate = {2014-01-01},

journal = {Archives de Pédiatrie},

volume = {21},

number = {5},

pages = {645},

publisher = {Elsevier},

keywords = {biostatistics},

pubstate = {published},

tppubtype = {article}

}